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Stem cells, scientific facts and fiction, edited by Christine Mummery, Anja Van De Stolpe, Bernard A.J. Roelen, Hans Clevers - (pbk.)

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"The second edition of Stem Cells: Scientific Facts and Fiction provides the non-stem cell expert with an understandable review of the history, current state of affairs, and facts and fiction of the promises of stem cells. Building on success of its award-winning preceding edition, the second edition features new chapters on embryonic and iPS cells and stem cells in veterinary science and medicine. It contains major revisions on cancer stem cells to include new culture models, additional interviews with leaders in progenitor cells, engineered eye tissue, and xeno organs from stem cells, as well as new information on "organs on chips" and adult progenitor cells. In the past decades our understanding of stem cell biology has increased tremendously. Many types of stem cells have been discovered in tissues that everyone presumed were unable to regenerate in adults, the heart and the brain in particular. There is vast interest in stem cells from biologists and clinicians who see the potential for regenerative medicine and future treatments for chronic diseases like Parkinson's, diabetes, and spinal cord lesions, based on the use of stem cells; and from entrepreneurs in biotechnology who expect new commercial applications ranging from drug discovery to transplantation therapies."--Publisher information

Table of contents

The biology of the cell -- Embryonic development -- What are stem cells? -- Of mice and men : the history of embryonic stem cells -- Origins and types of stem cells : what's in a name? -- Cloning : history and current applications -- Regenerative medicine : clinical applications of stem cells -- Stem cells in veterinary medicine -- Cardiomyocytes from stem cells : what can we do with them? -- Adult stem cells : generation of self-organizing mini-organs in a dish -- Stem cell tourism -- Cancer stem cells : where do they come from and where are they going? -- Human stem cells for organs-on-chips : clinical trials without patients? -- Stem cells for discovery of effective and safe new drugs -- Patents, opportunities, and challenges : legal and intellectual property issues associated with stem cells -- Stem cell perspectives : a vision of the future

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