Bibliograph

RNA, life's indispensable molecule, James Darnell

Type

Label

RNA, life's indispensable molecule, James Darnell

Language

eng

Bibliography note

Includes bibliographical references (pages 397-398) and index

Illustrations

illustrations

Index

index present

Literary Form

non fiction

Main title

RNA

Nature of contents

bibliography

Oclc number

698029439

Responsibility statement

James Darnell

Sub title

life's indispensable molecule

Summary

In this textbook the author provides an account of RNA research, illuminated by his own life-long engagement in the field. He describes how scientists unraveled fundamental questions about the biochemical and genetic importance of RNA, how mRNAs are generated and used to produce proteins, how noncoding and catalytic RNAs mediate key cellular processes, and how RNA molecules likely initiated life on Earth. With a scope extending from the early 20th century to the present day, he conveys the intellectual context in which these questions first arose and explains how the key experiments were structured and answers obtained. The book is geared towards scientists from the graduate level on up

Table Of Contents

Pursuing RNA for more than 50 years -- The dawn of molecular biology : history of macromolecules before RNA -- RNA connects genes and proteins : ribosomes, tRNA, and messenger RNA -- After mRNA : the genetic code, translation, and the biochemistry of controlled RNA synthesis in bacteria -- Gene expression in mammalian cells : discovery of RNA processing, genes in pieces, and new RNA chemistry -- Controlling mRNA : the cell's most complicated task -- RNA and the beginning of life

Classification