The Resource Rigor mortis : how sloppy science creates worthless cures, crushes hope, and wastes billions, Richard Harris
Rigor mortis : how sloppy science creates worthless cures, crushes hope, and wastes billions, Richard Harris
Resource Information
The item Rigor mortis : how sloppy science creates worthless cures, crushes hope, and wastes billions, Richard Harris represents a specific, individual, material embodiment of a distinct intellectual or artistic creation found in Waubonsee Community College.This item is available to borrow from 1 library branch.
Resource Information
The item Rigor mortis : how sloppy science creates worthless cures, crushes hope, and wastes billions, Richard Harris represents a specific, individual, material embodiment of a distinct intellectual or artistic creation found in Waubonsee Community College.
This item is available to borrow from 1 library branch.
- Summary
- "Biomedical science--the research that underlies our treatments and cures--is in deep crisis. Every year, American taxpayers spend more than $30 billion funding it. About half of that work, by some estimates, is wrong. As award-winning science journalist Richard Harris reveals in Rigor Mortis, this is not simply the result of trial and error, which is an essential part of the scientific process. The economic imperative for researchers to get and keep jobs and funding encourages dubious behavior, from poor experimental design to sloppy statistics and shoddy analysis. Add to that a bunch of mislabeled cell lines and mishandled ingredients, and what seems like a potential cure becomes an unreliable mess. Some 900 breast-cancer studies were conducted with cells that weren't breast-cancer cells at all, new "treatments" for ALS developed in rodent models failed when retested properly in mice, and only 1.2 percent of early papers in genomics stand the test of time. These problems aren't the exception. They are commonplace. This crisis of reproducibility--when studies done in one lab fail when another tries to reproduce their results--isn't just holding back scientific progress--it's a devastating blow for patients everywhere who are hoping that medical science will give them longer, healthier lives. Rigor Mortis explores these urgent issues through vivid anecdotes, personal stories, and interviews with the nation's top biomedical researchers, some of whom are now struggling to set things right. An unsparing investigation that lays bare the dysfunctions in our research system, this book represents the first step toward fixing it."--Jacket
- Language
- eng
- Extent
- vii, 278 pages
- Contents
-
- Begley's bombshell
- It's hard even on the good days
- A bucket of cold water
- Misled by mice
- Trusting the untrustworthy
- Jumping to conclusions
- Show your work
- A broken culture
- The challenge of precision medicine
- Inventing a discipline
- Isbn
- 9780465097906
- Label
- Rigor mortis : how sloppy science creates worthless cures, crushes hope, and wastes billions
- Title
- Rigor mortis
- Title remainder
- how sloppy science creates worthless cures, crushes hope, and wastes billions
- Statement of responsibility
- Richard Harris
- Language
- eng
- Summary
- "Biomedical science--the research that underlies our treatments and cures--is in deep crisis. Every year, American taxpayers spend more than $30 billion funding it. About half of that work, by some estimates, is wrong. As award-winning science journalist Richard Harris reveals in Rigor Mortis, this is not simply the result of trial and error, which is an essential part of the scientific process. The economic imperative for researchers to get and keep jobs and funding encourages dubious behavior, from poor experimental design to sloppy statistics and shoddy analysis. Add to that a bunch of mislabeled cell lines and mishandled ingredients, and what seems like a potential cure becomes an unreliable mess. Some 900 breast-cancer studies were conducted with cells that weren't breast-cancer cells at all, new "treatments" for ALS developed in rodent models failed when retested properly in mice, and only 1.2 percent of early papers in genomics stand the test of time. These problems aren't the exception. They are commonplace. This crisis of reproducibility--when studies done in one lab fail when another tries to reproduce their results--isn't just holding back scientific progress--it's a devastating blow for patients everywhere who are hoping that medical science will give them longer, healthier lives. Rigor Mortis explores these urgent issues through vivid anecdotes, personal stories, and interviews with the nation's top biomedical researchers, some of whom are now struggling to set things right. An unsparing investigation that lays bare the dysfunctions in our research system, this book represents the first step toward fixing it."--Jacket
- Cataloging source
- DLC
- http://library.link/vocab/creatorName
- Harris, Richard F
- Dewey number
- 610.72
- Index
- index present
- LC call number
- R852
- LC item number
- .H37 2017
- Literary form
- non fiction
- Nature of contents
- bibliography
- NLM call number
- W 20.5 (H)
- http://library.link/vocab/subjectName
-
- Medicine
- Medical ethics
- Medical ethics
- MEDICAL
- MEDICAL
- SCIENCE
- Medical ethics
- Medicine
- Biomedical Research
- Biomedical Research
- Biomedical Research
- Label
- Rigor mortis : how sloppy science creates worthless cures, crushes hope, and wastes billions, Richard Harris
- Bibliography note
- Includes bibliographical references (pages 239-264) and index
- Carrier category
- volume
- Carrier category code
-
- nc
- Carrier MARC source
- rdacarrier
- Content category
- text
- Content type code
-
- txt
- Content type MARC source
- rdacontent
- Contents
- Begley's bombshell -- It's hard even on the good days -- A bucket of cold water -- Misled by mice -- Trusting the untrustworthy -- Jumping to conclusions -- Show your work -- A broken culture -- The challenge of precision medicine -- Inventing a discipline
- Control code
- ocn958798220
- Dimensions
- 22 cm
- Extent
- vii, 278 pages
- Isbn
- 9780465097906
- Lccn
- 2017001183
- Media category
- unmediated
- Media MARC source
- rdamedia
- Media type code
-
- n
- System control number
-
- (Sirsi) i9780465097906
- (OCoLC)958798220
- Label
- Rigor mortis : how sloppy science creates worthless cures, crushes hope, and wastes billions, Richard Harris
- Bibliography note
- Includes bibliographical references (pages 239-264) and index
- Carrier category
- volume
- Carrier category code
-
- nc
- Carrier MARC source
- rdacarrier
- Content category
- text
- Content type code
-
- txt
- Content type MARC source
- rdacontent
- Contents
- Begley's bombshell -- It's hard even on the good days -- A bucket of cold water -- Misled by mice -- Trusting the untrustworthy -- Jumping to conclusions -- Show your work -- A broken culture -- The challenge of precision medicine -- Inventing a discipline
- Control code
- ocn958798220
- Dimensions
- 22 cm
- Extent
- vii, 278 pages
- Isbn
- 9780465097906
- Lccn
- 2017001183
- Media category
- unmediated
- Media MARC source
- rdamedia
- Media type code
-
- n
- System control number
-
- (Sirsi) i9780465097906
- (OCoLC)958798220
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<div class="citation" vocab="http://schema.org/"><i class="fa fa-external-link-square fa-fw"></i> Data from <span resource="http://link.library.waubonsee.edu/portal/Rigor-mortis--how-sloppy-science-creates/tm1oMNZeQT0/" typeof="Book http://bibfra.me/vocab/lite/Item"><span property="name http://bibfra.me/vocab/lite/label"><a href="http://link.library.waubonsee.edu/portal/Rigor-mortis--how-sloppy-science-creates/tm1oMNZeQT0/">Rigor mortis : how sloppy science creates worthless cures, crushes hope, and wastes billions, Richard Harris</a></span> - <span property="potentialAction" typeOf="OrganizeAction"><span property="agent" typeof="LibrarySystem http://library.link/vocab/LibrarySystem" resource="http://link.library.waubonsee.edu/"><span property="name http://bibfra.me/vocab/lite/label"><a property="url" href="http://link.library.waubonsee.edu/">Waubonsee Community College</a></span></span></span></span></div>
